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Can Bipolar Turn To Schizophrenia

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Cause Of Schizoaffective Disorder Is Unknown

What is the difference between schizophrenia, schizoaffective disorder, and bipolar disorder?

Most mental health experts believe that schizoaffective disorder is a variation of schizophrenia, but the exact cause remains unclear. Current theory suggests that schizoaffective disorder is triggered by a range of factors working in combination including:

  • genetic susceptibility
  • environmental factors such as stress
  • differences in brain chemical and receptor interactions.

Molecular Genetic Studies Of Schizoaffective Disorder

As discussed above, most studies include schizoaffective disorder or its subtypes as adjunctive phenotypes, when the main focus of the study is schizophrenia or bipolar disorder. However, some studies have focused on individuals with schizoaffective disorder within these samples.

For example, a study of RDC schizoaffective disorder, bipolar subtype , found an association with markers in -aminobutyric acid A receptor genes, but no significant association with schizophrenia or bipolar disorder. This finding was replicated in an independent sample. If further investigation confirms this as a true association, it remains to be seen whether it is specific to the bipolar subtype of schizoaffective disorder or whether associations with schizophrenia and bipolar disorder become more evident, eg, with larger sample sizes.

Polygenic score analysis has also been applied to the RDC schizoaffective disorder bipolar subtype. Polygenic scores from schizophrenia were used to test differences between subphenotypes in 2 bipolar disorder samples. This study found that individuals with schizoaffective disorder bipolar subtype had higher scores than individuals with bipolar disorder, consistent with the polygenic influences on schizophrenia having a greater overlap with those for schizoaffective disorder bipolar subtype than with those for bipolar disorder.

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Can Psychotic Depression Lead To More Complications Such As Schizophrenia

As weve explored already, depression is a disorder of a different kind and category than schizophrenia. This means that depression does not ultimately evolve into schizophrenia. But there are overlaps in symptoms and side effects with the two disorders, and it is possible for someone to have both disorders at once. When someone has co-occurring depression and schizophrenia, it has a unique diagnosis: schizoaffective disorder. This dual diagnosis is important because it informs the level of integrated treatment someone needs.

Even without the occurrence of a psychotic disorder, when depression is particularly severe, it is possible for a person to experience distortions in their reality, including psychotic symptoms. An important difference is that someone with schizophrenia who experiences a psychotic episode inherently believes that their delusions or hallucinations are part of reality someone who experiences a psychotic episode in connection with severe depression often has a better grip on their actual reality and can clue into the discrepancies there.

This understanding of the disconnect between what they are perceiving and the reality they know does not necessarily diminish their distress and confusion. On the contrary, this awareness can bring its own overwhelming complications. It can add to a persons anxiety and their feelings of shame, unworthiness, hopelessness, and lack of confidence.

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How Schizoaffective Disorder Is Treated

Despite advanced symptom tracking technologies and data collection, there is no apparent cause of schizoaffective disorder. Despite this, professionals have come up with successful treatment plans that improve patients quality of life.

The following methods can help alleviate symptoms:

  • Medication: Currently, the only FDA-approved drug for treating schizoaffective disorder is Invega, which helps subdue episodes and reduce erratic moods that may lead to suicide attempts. If youre considering a new type of medication, always consult with a doctor first.
  • Psychotherapy: Patients can undergo all forms of talk therapy, whether on their own, with family, or with other people who share similar experiences.
  • Life Skills Training: Through vocational rehabilitation and social skills training, a person improves their ability to participate in all activities, from daily tasks to social settings. Patients can learn how to prevent an episode through lifestyle adjustments and additional tools such as a meditation app or exercise program.

How Does It Affect People

Can Bipolar Turn Into Schizophrenia

Bipolar disorder affects both men and women. For many people, the first symptoms show up in their early twenties. However, research has shown that the first episode of bipolar disorder is occurring earlier: It often shows up in adolescence, and even children can have the disorder.

Recent research suggests that kids and teens with bipolar disorder dont always have the same behavioral patterns that adults with bipolar disorder do. For example, kids who have bipolar disorder may experience particularly rapid mood changes and may have some of the other mood-related symptoms listed below, such as irritability and high levels of anxiety. But they may not show other symptoms that are more commonly seen in adults.

Because brain function is involved, the ways people with bipolar disorder think, act, and feel are all affected. This can make it especially difficult for other people to understand their condition. It can be incredibly frustrating if other people act as though someone with bipolar disorder should just snap out of it, as if a person who is sick can become well simply by wanting to.

Bipolar disorder isnt a sign of weakness or a character flaw its a serious medical condition that requires treatment, just like any other condition.


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What If I Am A Carer Friend Or Relative

What support can I get?

You can get support if you care for someone with schizoaffective disorder. These are some options for you:

  • Family Intervention through the NHS
  • Join a carers service
  • Join a carers support group
  • Ask your local authority for a carers assessment
  • Read about the condition
  • Apply for welfare benefits for carers

Rethink Mental Illness run carers support groups in some areas. You can also search for groups on the Carers Trust website:

Rethink Mental Illness: www.rethink.org/about-us/our-support-groups Carers Trust www.carers.org/search/network-partners

How can I support the person I care for?

You might find it easier to support someone with schizoaffective disorder if you understand their symptoms, treatment and self-management skills.

You should be aware of what you can do if you are worried about their mental state or risk of self-harm. It can be helpful to know contact information for their mental health team or GP.

You could find out from your relative if they have a crisis plan. You could help your relative to make a crisis plan if they dont have one.

You can find out more information about:

What Happens If Bpd Is Left Untreated

If left untreated, the effects of borderline personality can be devastating, not only for the individual who is diagnosed with the disorder, but their friends and family as well. Some of the most common effects of untreated BPD can include the following: Dysfunctional social relationships. Repeated job losses.

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What Medications Treat Schizoaffective Disorder

The provider will figure out the right medicine based on the type of mood disorder the person has:

  • Antipsychotics: This is the primary medicine used to treat the psychotic symptoms that come with schizophrenia for example, delusions, hallucinations and disordered thinking.
  • Antidepressants: An antidepressant or mood stabilizer such as lithium can help treat mood-related symptoms. Sometimes, a person needs both an antidepressant and an antipsychotic.

Treatment Options For Schizoaffective Disorder

Confessions of a Bipolar Schizophrenic

A multi-faceted treatment program is generally recommended for schizoaffective disorder, including:

  • medications antipsychotic medications are usually given first. Antidepressant or mood stabilising medications are used once the psychotic symptoms are under control. Sometimes antipsychotic medications and antidepressants are used at the same time. Anticonvulsant medication can also help treat mood disorder symptoms
  • electroconvulsive therapy is used to treat depression by inducing controlled seizures via small electrodes placed at specific locations on the head
  • psychological therapy which usually includes learning practical strategies to help avoid or identify future episodes
  • psychosocial counselling to help the person avoid the common pitfalls of mental illness such as unemployment, poverty and loneliness
  • support from family and friends understanding and support from loved ones is very important. Family and friends are advised to learn as much as they can about schizoaffective disorder to help the affected person and themselves. Support groups and counselling services are available for relatives and friends of people with mental illness.

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What Causes These Disorders

After years of research, doctors still dont know what causes schizophrenia. They think that chemical imbalances of dopamine and glutamate might play a role. Also, they know that people with schizophrenia often have physically different brains than those who dont. This might indicate that it happens during the development of the brain itself.

Doctors havent studied schizoaffective disorder for nearly as long. However, theyve made more breakthroughs. For example, doctors believe that the genes that control the bodys natural sleep and wake cycle contribute to this disorder.

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What Should You Not Say To Someone With Bipolar

9 Things Not to Say to Someone Who Has Bipolar DisorderYoure Just Overreacting AgainAnything That Doesnt Kill You Makes You StrongerEverybody Has Mood Swings SometimesEveryone Is a Little Bipolar SometimesYou Are PsychoYoure Acting Like a ManiacI Wish I Was Manic so I Could Get Things DoneMore items

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Study Design And Data

This study uses data from the MERTTU research project, the background and methodology of which have been reported in detail elsewhere.- In our study, the data are based on the Finnish Hospital Discharge Register , maintained by the Finnish Institute of Health and Welfare, which includes all psychiatric and somatic hospitalizations since 1969, and the Causes of Death Register of Statistics Finland. Permission to use the data was provided by the registers. FHDR includes data on, for example, admission and discharge dates, diagnoses, operations, hospital, and specialty quality of data in the register is known to be good. Since 1994, also information on psychiatric admissions, including data on treatments and admission as well as status of overall functioning, has been collected. The overall functioning is assessed by the attending doctor using the Global Assessment Scale . The Finnish personal identity codes enabled us to connect these registers at the individual level, resulting in a comprehensive dataset on all inpatient psychiatric hospitalizations from 1980 to 2011. No private psychiatric hospitals exist in Finland. No data on outpatient settings were available for the current study.

Risk Factors For Bipolar Disorder And Schizophrenia


No one knows what causes bipolar disorder or schizophrenia. However, genetics are probably a risk factor, as both conditions likely run in families. This doesnt mean that youll definitely inherit the disorder if your parent or sibling has it. Your risk increases, however, if multiple family members have the disorder. But knowing theres a risk increases the chance of early detection and treatment.

Environmental factors may also contribute to your risk, but this connection isnt entirely understood yet.

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Causes Of Schizoaffective Disorder

Scientists donât know the exact cause. Risk factors for schizoaffective disorder include:

  • Genetics: You may inherit a tendency to get features linked to schizoaffective disorder from your parents.
  • Brain chemistry and structure: If you have schizophrenia and mood disorders, you might have problems with brain circuits that manage mood and thinking. Schizophrenia is also tied to lower levels of dopamine, a brain chemical that also helps manage these tasks.
  • Environment: Some scientists think things like viral infections or highly stressful situations could play a part in getting schizoaffective disorder if youâre at risk for it. How that happens isnât clear.
  • Drug use: Taking mind-altering drugs.

Schizoaffective disorder usually begins in the late teen years or early adulthood, often between ages 16 and 30. It seems to happen slightly more often in women than in men. It’s rare in children.

Because schizoaffective disorder combines symptoms that reflect two mental illnesses, itâs easily confused with other psychotic or mood disorders. Some doctors may diagnose schizophrenia. Others may think itâs a mood disorder. As a result, itâs hard to know how many people actually have schizoaffective disorder. Itâs probably less common than either schizophrenia or mood disorders alone.

Genetic Influences On The Individual Disorders

Prior to consideration of genetic relationships between schizophrenia, bipolar, and schizoaffective disorders, it is relevant to summarize the evidence for genetic influences on the individual disorders.

Results of family, twin, and adoption studies show a notably similar pattern for each disorder. Traditional family studies conducted during the 20th century based on clinically ascertained samples show substantial familial aggregation, with sibling relative risks of around 810 for schizophrenia, bipolar disorder, and schizoaffective disorder.,, More recently, considerably larger studies, based on Scandinavian national population registers, have substantiated the results of the earlier family studies.,, Results from the largest study, based on over 2 million families, are shown in .

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Bipolar Disorder Vs Schizophrenia

How Close Is Bipolar To Schizophrenia

Catatonic Schizophrenia- Can schizophrenia make you slow?

schizophrenia facts. Bipolar disorder is an illness that involves mood swings with at least one episode of mania and may also involve repeated episodes of depression. Schizophrenia is a chronic, severe, debilitating mental illness characterized by psychotic symptoms, meaning that one is out of touch with reality.

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What You Can Do

People can often manage the symptoms of bipolar disorder and schizophrenia with medication and therapy. Having a support system in place will increase your chances of successfully managing your symptoms. A support system may include family, friends, and the people in your workplace.

If you have either bipolar disorder or schizophrenia, you have an increased risk of suicide. See your doctor if you have thoughts of suicide. They can provide treatment. Support groups can help to reduce the risk of suicide. You should also avoid alcohol and drugs to further reduce your risk.

If you have bipolar disorder, you should do the following:

  • Follow a relatively stable lifestyle.
  • Get an adequate amount of sleep.
  • Maintain a healthy diet.

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What If Adhd Is Left Untreated

Untreated ADHD in an adult can lead to significant problems with education, social and family situations and relationships, employment, self-esteem, and emotional health. It is never too late to recognize, diagnose, and treat ADHD and any other mental health condition that can commonly occur with it.

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Rose Hill Center Can Help You Overcome Both Disorders

While theres clearly a difference between these two disorders, it doesnt have to change where you get help. At Rose Hill Center, we understand the differences between the two. For that reason, we offer different treatment options at one location.

At Rose Hill Center, we strive to offer a variety of treatment services for mental health problems. A few of these include:

Cumulative Incidence And Its Temporal Patterns For Diagnostic Conversion From Ud To Bd Schizophrenia And Sad

How do schizoaffective and schizophrenia disorders compare ...

In our study, the cumulative incidence of conversion from UD to BD during a 15-year follow-up is lower that reported in the meta-analyses by Kessing et al and Ratheesh et al but in line with the findings from the largest register-based study of Musliner et al showing a 21-year cumulative incidence of conversion of 8.7% in women and 7.7% in men. Notably, although relatively low lifetime prevalence of BD has been reported in Finland,, the cumulative conversion incidence is comparable to the conversion risk reported in Denmark. However, the conversion incidence to schizophrenia was approximately two and half times lower than in the Danish register study. Since lifetime prevalence of schizophrenia in Finland was reported to be even higher than in other Nordic countries,, this finding is unexpected. We presume that the lack of data on outpatient units and private settings, the register-based design, and the exclusion of patients with previous hospitalizations due to unspecified psychosis may partly explain this discrepancy. In addition, slight differences may exist in the mental health service structures between these countries.

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What Is Schizoaffective Disorder

People with schizoaffective disorder experience the same symptoms as schizophrenic patients and those with mood-related illnesses such as Bipolar Type I or II. In the United States, only 0.3% of people demonstrate these traits. While schizoaffective occurs equally in men and women, men are more likely to develop the illness in childhood or adolescence.

Some individuals with this disorder are depressive, while some are manic. Symptoms can either be mild or severe, with patients experiencing a mood episode several times a week. A person might also have disorganized speech, behavior, and thoughts.

Diagnosis Of Schizoaffective Disorder

There are no laboratory tests to specifically diagnose schizoaffective disorder. So doctors rely on your medical history and your answers to certain questions. They also use various tests such as brain imaging and blood tests to make sure that another type of illness isnât causing your symptoms.

If the doctor finds no physical cause, they may refer you to a psychiatrist or psychologist. These mental health professionals are trained to diagnose and treat mental illnesses. They use specially designed interview and assessment tools to evaluate a person for a psychotic disorder.

In order to get diagnosed with schizoaffective disorder, you must have:

  • Periods of uninterrupted illness
  • An episode of mania, major depression, or a mix of both
  • Symptoms of schizophrenia
  • At least two periods of psychotic symptoms, each lasting 2 weeks. One of the episodes must happen without depressive or manic symptoms.

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